TRIM: Danish Form and Dose Study on Vitamin B12

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Dietary Supplement: Vitamin B12

• Registration Number: NCT02832726
• Lead Sponsor: University of Aarhus

Brief Summary

The study investigates the absorption of different doses of hydroxocobalamin and cyanocobalamin in a vitamin B12-replete Danish population.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01
• Primary Completion: 2016-05
• Status Verified: 2016-06
• Study Completion: 2016-06
• Study First Submitted: 2016-06-28
• Study First Submitted QC: 2016-07-11
• Last Update Submitted: 2016-07-11
• Study First Posted: 2016-07-14
• Last Update Posted: 2016-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• At least 18 years old

Read More

Exclusion Criteria

• Use of vitamin pills with vitamin B12 within the last two weeks of the study
• Treatment with vitamin B12 injections within the last year
• Known chronic systemic disease
• Not able to give informed consent.

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
cyano-hydroxo B12	Vitamin B12	Absorption of 3 doses of 9 ug cyano-B12 and 9 ug hydroxo-B12 for two days (the CobaSorb test). No drugs given.
Cyano-B12 doses	Vitamin B12	Absorption of 3 doses of 3 ug, 6 ug, and 9 ug cyano-B12 for two days (the CobaSorb test). No drugs given.

Primary Outcome Measures

Name	Time	Method
Vitamin B12 absorption (increase in holotranscobalamin)	3 days