Epidemiology of multiresistant gram-negative bacteria (MRGN) in the context of hospital treatment at university hospital Jena – a prospective cohort study
- Conditions
- Within the study no specific disease pattern is investigated.
- Registration Number
- DRKS00005273
- Lead Sponsor
- niversitätsklinikum Jena Zentrum für Infektionsmedizin und Krankenhaushygiene
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 1499
Inclusion Criteria
at least age of 18 years
- expected hospitalisation more than 48 hours
- admission from extern
Exclusion Criteria
not any
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Rate of colonisation [n/1000 patients] with MRGN during hospital stay via quotient from number of patients that are colonised with a new MRGN bacteria at hospital discharge by number of total patients at hospital discharge
- Secondary Outcome Measures
Name Time Method -Rate of nosocomial infection during hospital stay (Total, With MRGN (PFGE analysis), Selective for Full-Analysis-Setnegativ and Full-Analysis-SetMRGN)<br>-Acquirement of MRGN per 1000 antibiotic-days in hospital (per class of antibiotics, per substance, per antibiotic combination)<br>-Rate of colonisation with MRGN from that patients that are colonised with MRGN at hospital discharge (via quotient from patients that are colonised with MRGN at 6 month after hospital discharge by number of patients that are colonised at hospital discharge)<br>-clonality of all detected MRGN (PFGE-analysis)<br>