Laparoscopic Complete Mesocolic Excision on Colon Cancer

Not Applicable

Completed

• Conditions: Operation Finding; Complications; Pathology; Quality of Life; Neoplasms Recurrence
• Interventions: Procedure: laparoscopic complete mesocolic excision; Procedure: D3-laparoscopic colectomy

• Registration Number: NCT01628250
• Lead Sponsor: Bo Feng

Brief Summary

Laparoscopic complete mesocolic excision is a concept that using laparoscopic surgery technique to perform a resection for colon cancer. Besides, the segment of the colon containing the tumor, the resection area should include an intact mesocolon as an envelope to encase the possible route for metastasis. The routes include blood vessels, lymphatic drain and etc. Such hypothesis predicts better histopathological and higher oncological results which turns into better survival rate and better quality of life.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-06
• Study First Submitted: 2012-06-20
• Study First Submitted QC: 2012-06-22
• Study First Posted: 2012-06-26
• Primary Completion: 2015-10
• Study Completion: 2015-10
• Results First Submitted: 2015-11-07
• Results First Submitted QC: 2016-05-21
• Results First Posted: 2016-06-29
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-26
• Last Update Posted: 2022-11-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 99

Inclusion Criteria

• Patients with pathologically confirmed colon cancer
• Signed consent

Exclusion Criteria

• History of malignancy
• Intestinal obstruction or perforation
• Evidence of metastasis by preoperative examinations
• Deformity of spine
• Emergency case
• BMI > 29

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
laparoscopic complete mesocolic excision	laparoscopic complete mesocolic excision	Randomized group of patients receiving laparoscopic colectomy with the concept of complete mesocolic excision
D3 laparoscopic colectomy	D3-laparoscopic colectomy	Randomized group of patients receiving laparoscopic colectomy with D3-resection

Primary Outcome Measures

Name	Time	Method
Histopathological Outcomes Obtained Through the Surgeries	14 days after the surgery	number of lymph nodes retrieved

Secondary Outcome Measures

Name	Time	Method
Survival Rate	3 years after the surgery	The follow up to the patients after the surgery to evaluate the oncological results of the technique

Trial Locations

Locations (1)

Ruijin Hospital affiliated to Shanghai Jiaotong University school of medicine; 🇨🇳 Shanghai, Shanghai, China