An observational study on assessment of coagulation abnormalities in critically ill patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- Mortality in ICU patients.
研究概览
简要总结
This observational study aims to evaluate the prevalence, types, and clinical significance of coagulation abnormalities in critically ill patients admitted to the Intensive Care Unit (ICU). Coagulation disturbances are common in ICU settings due to underlying conditions such as sepsis, liver dysfunction, trauma, and the effects of various therapeutic interventions. The study will involve systematic assessment of coagulation parameters including prothrombin time (PT), activated partial thromboplastin time (aPTT), platelet counts , D-dimer, fibrinogen levels and Thromboelastography (TEG) in ICU patients over a specified period. Correlation between coagulation abnormalities and clinical outcomes such as bleeding, thrombosis, length of ICU stay, and mortality will also be analyzed. The findings are expected to provide insights into the importance of routine coagulation monitoring and guide early intervention strategies to improve patient outcomes.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •Invasive procedure and Significant trauma.
排除标准
- •Patients with known stable chronic thrombocytopenia and patients with isolated vitamin K deficiency.
结局指标
主要结局
Mortality in ICU patients.
时间窗: 4 weeks
次要结局
- Need for interventions based on the abnormality.(4 weeks)
研究者
Rakshaya shree G
Sri ramachandra institute of higher education and research
