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临床试验/CTRI/2025/07/091005
CTRI/2025/07/091005尚未招募不适用

An observational study on assessment of coagulation abnormalities in critically ill patients

Sri Ramachandra Institute of Higher Education and Research1 个研究点 分布在 1 个国家目标入组 108 人开始时间: 2025年8月4日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
108
试验地点
1
主要终点
Mortality in ICU patients.

研究概览

简要总结

This observational study aims to evaluate the prevalence, types, and clinical significance of coagulation abnormalities in critically ill patients admitted to the Intensive Care Unit (ICU). Coagulation disturbances are common in ICU settings due to underlying conditions such as sepsis, liver dysfunction, trauma, and the effects of various therapeutic interventions. The study will involve systematic assessment of coagulation parameters including prothrombin time (PT), activated partial thromboplastin time (aPTT), platelet counts , D-dimer, fibrinogen levels and Thromboelastography (TEG) in ICU patients over a specified period. Correlation between coagulation abnormalities and clinical outcomes such as bleeding, thrombosis, length of ICU stay, and mortality will also be analyzed. The findings are expected to provide insights into the importance of routine coagulation monitoring and guide early intervention strategies to improve patient outcomes.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Invasive procedure and Significant trauma.

排除标准

  • Patients with known stable chronic thrombocytopenia and patients with isolated vitamin K deficiency.

结局指标

主要结局

Mortality in ICU patients.

时间窗: 4 weeks

次要结局

  • Need for interventions based on the abnormality.(4 weeks)

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Rakshaya shree G

Sri ramachandra institute of higher education and research

研究点 (1)

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