An observational study on assessment of coagulation abnormalities in critically ill patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 108
- Locations
- 1
- Primary Endpoint
- Mortality in ICU patients.
Study Overview
Brief Summary
This observational study aims to evaluate the prevalence, types, and clinical significance of coagulation abnormalities in critically ill patients admitted to the Intensive Care Unit (ICU). Coagulation disturbances are common in ICU settings due to underlying conditions such as sepsis, liver dysfunction, trauma, and the effects of various therapeutic interventions. The study will involve systematic assessment of coagulation parameters including prothrombin time (PT), activated partial thromboplastin time (aPTT), platelet counts , D-dimer, fibrinogen levels and Thromboelastography (TEG) in ICU patients over a specified period. Correlation between coagulation abnormalities and clinical outcomes such as bleeding, thrombosis, length of ICU stay, and mortality will also be analyzed. The findings are expected to provide insights into the importance of routine coagulation monitoring and guide early intervention strategies to improve patient outcomes.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 99.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Invasive procedure and Significant trauma.
Exclusion Criteria
- •Patients with known stable chronic thrombocytopenia and patients with isolated vitamin K deficiency.
Outcomes
Primary Outcomes
Mortality in ICU patients.
Time Frame: 4 weeks
Secondary Outcomes
- Need for interventions based on the abnormality.(4 weeks)
Investigators
Rakshaya shree G
Sri ramachandra institute of higher education and research
