Celecoxib add on therapy in drug naive depressed wome
Phase 3
- Conditions
- major depressive disorder.Depressive episode
- Registration Number
- IRCT201009043106N3
- Lead Sponsor
- Pharmaceutical Sciences Branch of Islamic Azad university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
1. women experiencing first episode of depression according to DSM-IV-TR and the Hamilton rating scale (17 items) score was ranged from 18 to 36. 2. None of them had previously received antidepressant treatment. Exclusion criteria: 1. History of taking antidepressant medications. 2. Other psychiatric disorders. 3. Significant suicidal ideation. 4. lactation and pregnancy. 5. Liver and kidney dysfunction and cardiovascular disorders. 6. Drug abuse.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression severity. Timepoint: baseline, week 4 and week 8. Method of measurement: Hamilton Depression rating scale -17 items.;Anxiety severity. Timepoint: baseline, week 4 and week 8. Method of measurement: Hamilton Anxiety rating scale.
- Secondary Outcome Measures
Name Time Method General health level. Timepoint: baseline, week 4 and week 8. Method of measurement: General health questionnair-28.