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Clinical Trials/NCT06327061
NCT06327061
Recruiting
Not Applicable

A Social Diffusion Fatal Overdose Prevention Intervention: Assessing the Effectiveness of People Who Use Opioids as Peer Educators in Training Using & Non-using Networks on Overdose & Stigma Reduction

Johns Hopkins Bloomberg School of Public Health1 site in 1 country600 target enrollmentJune 1, 2024

Overview

Phase
Not Applicable
Intervention
Network overdose prevention
Conditions
Drug Overdose
Sponsor
Johns Hopkins Bloomberg School of Public Health
Enrollment
600
Locations
1
Primary Endpoint
Participant drug use
Status
Recruiting
Last Updated
last month

Overview

Brief Summary

The purpose of this study is to test a social intervention focused on overdose prevention and care. In the investigators prior work, the investigators have shown that people who use opioids (PWUO) can be effective peer educators (PEs).

Detailed Description

The purpose of this study is to test a social intervention focused on overdose prevention and care. In the investigators prior work, the investigators have shown that people who use opioids (PWUO) can be effective peer educators (PEs). The investigators have utilized PEs for overdose prevention in interventions that have focused on training network members who use drugs to respond to an overdose. Yet, many overdoses are witnessed by people who do not use drugs. Additionally, many PWUO report using drugs at home and living with someone who does not use drugs, which highlights the importance of training non-using network members on overdose response. Based on pilot data, the investigators propose expanding an overdose peer education intervention to focus on non-using network members. The intervention seeks to prepare network members to respond to an overdose and normalize discussions about overdose prevention planning between index PWUO and non-using network members. The intervention condition consists of 3 individual sessions focused on overdose prevention and response. This condition is designed to train index study participants to be Peer Educators. In addition to the three sessions, the non-drug using network member will be offered one session. The control condition is only 1 session focused on overdose prevention and response. Both intervention and control participants will invite social network members to take part in data collection activities

Registry
clinicaltrials.gov
Start Date
June 1, 2024
End Date
April 1, 2029
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • self-reported illicit opioid use at least 2 times in the past two weeks;
  • age 18 and older;
  • living in the Baltimore metropolitan region;
  • willing to engage in peer education; and
  • having and willing to recruit at least one non-using network member.

Exclusion Criteria

  • Participants without the cognitive ability to provide informed consent and have the physical ability to participate in in-person intervention sessions.

Arms & Interventions

Experimental: Peer education and network support

During sessions 1 and 2, participants will be taught information and skills pertaining to overdose prevention and response. During the 3rd session, participants will trained to talk to their non drug using network members in overdose prevention and response.

Intervention: Network overdose prevention

comparison: Standard of care of health education

In one session, participants will receive the standard of care for overdose prevention.

Intervention: Standard of care health education

Outcomes

Primary Outcomes

Participant drug use

Time Frame: 3-months

Proportion of times participants tested positive for drugs of fentanyl and xylazine using test strips in the prior 3 months.

Number of drug overdoses

Time Frame: 3-months

Number of drug overdoses in prior three months

Secondary Outcomes

  • Number of Network member contacts(3-months)

Study Sites (1)

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