Research and System Development on Functional 3D Optical Tomography for Skin Cell Imaging

• Conditions: Optical Coherence Tomography; Skin Cell Imaging

• Registration Number: NCT01557205
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The investigators will obtain human skin specimen (sized approximately 1 cm x 1 cm) for dermatological surgical patients in National Taiwan University Hospital, after informed consent was obtained. Human skin keratinocytes, fibroblasts, and melanocytes will be cultured from the human skin specimen. The three dimensional images of these cultured cells will be observed by a ultra-high resolution 3-dimensional optical coherence tomography.

Detailed Description

The investigators will obtain human skin specimen (sized approximately 1 cm x 1 cm) for dermatological surgical patients in National Taiwan University Hospital, after informed consent was obtained. Human skin keratinocytes, fibroblasts, and melanocytes will be cultured from the human skin specimen. The three dimensional images of these cultured cells will be observed by a ultra-high resolution 3-dimensional optical coherence tomography.

Study Timeline

• Status Verified: 2012-03
• Study Start: 2012-03
• Study First Submitted: 2012-03-15
• Study First Submitted QC: 2012-03-16
• Last Update Submitted: 2012-03-16
• Study First Posted: 2012-03-19
• Last Update Posted: 2012-03-19
• Primary Completion: 2013-04
• Study Completion: 2013-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Aged between 20 to 100.
• People who received benign skin tumor removal in dermatological surgical unit. OR
• People who received skin grafts (full thickness or split thickness) for reconstruction of surgical wounds after removing malignant skin cancer.

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Exclusion Criteria

• Age less than 20 years old,
• Psychiatric patients,
• Pregnant women.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified