The Effect of Exercise on Cognitive Status in Older Adults

Not Applicable

Completed

• Conditions: Older People
• Interventions: Other: Aerobic exercise training combined with dual-task training and lower limb strengthening; Other: Only lower limb strengthening group (CG); Other: Aerobic exercise training combined with lower limb strengthening; Other: Dual-task training combined with lower limb strengthening group (DG)

• Registration Number: NCT05532371
• Lead Sponsor: Muğla Sıtkı Koçman University

Brief Summary

The purpose of the study is to demonstrate the effectiveness of the different combinations of exercises on the cognitive status of older adults with cognitive decline.

Detailed Description

This study is planned to examine the effects of combined exercise on cognitive status, lower extremity muscle strength, mobility, physical performance, mood and quality of life in older adults with Mild Cognitive Impairment. Aerobic exercise training and lower limb (extremity) strengthening exercises were applied to the first group, dual-task training and lower limb strengthening exercises were applied to the second group, and aerobic exercise training, dual-task training and lower limb strengthening exercises were applied to the third group.

Study Timeline

• Study Start: 2019-01-30
• Primary Completion: 2019-12-01
• Study Completion: 2020-02-01
• Status Verified: 2022-09
• Study First Submitted: 2022-09-04
• Study First Submitted QC: 2022-09-04
• Last Update Submitted: 2022-09-04
• Study First Posted: 2022-09-08
• Last Update Posted: 2022-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Not had a fall in the last six months.
• Older adults with an mini mental state examination score between18-23.
• Age ≥ 65years.

Exclusion Criteria

• having central nervous system pathology that will affect balance
• diagnosed with vestibular pathology,
• having deformities in the waist, hip, and knee joints,
• having lower extremity amputation,
• with lower extremity operation history,
• malignancy affecting the lower extremity,
• having moderate and severe congenital heart disease, coronary heart disease and cerebrovascular disease,
• participants who cannot cooperate,
• participants who use an assistive walking device,
• participants having vision problems.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aerobic exercise training combined with dual-task training and lower limb strengthening group (ADG)	Aerobic exercise training combined with dual-task training and lower limb strengthening	Aerobic exercise training combined with dual-task training and lower limb strengthening.
Only lower limb strengthening group (CG)	Only lower limb strengthening group (CG)	Only lower limb strengthening.
Aerobic exercise training combined with lower limb strengthening group (AG)	Aerobic exercise training combined with lower limb strengthening	Aerobic exercise training combined with lower limb strengthening.
Dual-task training combined with lower limb strengthening group (DG)	Dual-task training combined with lower limb strengthening group (DG)	Dual-task training combined with lower limb strengthening.

Primary Outcome Measures

Name	Time	Method
Activities-specific Balance Confidence Scale	12 weeks	Balance Confidence is evaluated by Activities-specific Balance Confidence Scale.
Short Physical Performance Battery	12 weeks	Physical performance is evaluated by Short Physical Performance Battery.
Mini-Mental State Examination	12 weeks	Cognitive status examination is applied with a simple test called "Mini-Mental State Examination".
Six-Minute Walk Test	12 weeks	Exercise capacity is evaluated by Six-Minute Walk Test.
Commander Power Track 2 Manual Tester	12 weeks	Muscle strength strength is carried out with "Commander Power Track 2 Manual Tester".
Single Leg Stance Test	12 weeks	Static balance is evaluated by Single Leg Stance Test
Hamilton Depression Rating Scale	12 weeks	Emotional status is evaluated by Hamilton Depression Rating Scale
Timed Up and Go Test	12 weeks	Functional mobility is evaluated by Timed Up and Go Test.
World Health Organization Quality of Life-Old module	12 weeks	Quality of life is evaluated by World Health Organization Quality of Life-Old module

Trial Locations

Locations (1)

Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation; 🇹🇷 Ankara, Turkey