Efficacy of Cortex Stimulation in Neuropathic Pain

Phase 2

Terminated

• Conditions: Rebel Neuropathic Pains

• Registration Number: NCT00224666
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

The pains chronic neurogeneses remain difficult to treat whatever are their origin and their localization. The pharmacological therapeutic arsenal answers only partially the symptomatology often very invalidating which these chronic painful patients present. Electric stimulations of the central nervous system currently validated, in particular of the posterior cords of marrow made a significant improvement in a certain number of indications. Nevertheless, considerable patients are not relieved significantly, in particular those presenting of the pains neurogeneses of central origin (syndromes thalamic for example). It is within this framework that recently the stimulation of the sensorimotor cortex developed.

Principal objective: evaluation of the technique of stimulation under cortical on neuropathic pains .

Detailed Description

The pains chronic neurogeneses remain difficult to treat whatever are their origin and their localization. The pharmacological therapeutic arsenal answers only partially the symptomatology often very invalidating which these chronic painful patients present. Electric stimulations of the central nervous system currently validated, in particular of the posterior cords of marrow made a significant improvement in a certain number of indications. Nevertheless, considerable patients are not relieved significantly, in particular those presenting of the pains neurogeneses of central origin (syndromes thalamic for example). It is within this framework that recently the stimulation of the sensorimotor cortex developed.

Study Timeline

• Study Start: 2001-03
• Study First Submitted: 2005-09-16
• Study First Submitted QC: 2005-09-16
• Study First Posted: 2005-09-23
• Study Completion: 2005-11
• Status Verified: 2007-01
• Last Update Submitted: 2007-01-09
• Last Update Posted: 2007-01-11

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Neurofibromatosis,
• Rebel chronic neuropathic pain with duration > 1 year and AVS > = 4

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Exclusion Criteria

• Cancer
• Epilepsy
• Cognitive deterioration

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Efficacy of 50% of EVS at 3 weeks

Secondary Outcome Measures

Name	Time	Method
Efficacy of 50% of EVS at 6 months and 12 months

Trial Locations

Locations (1)

Hopital Henri Mondor; 🇫🇷 Creteil, France