Assessment of Modiff effect on xerostomia
Phase 2
- Conditions
- xerostomia.Disturbances of salivary secretion
- Registration Number
- IRCT2016092629998N1
- Lead Sponsor
- Salamat negar Hekmat pazhoohan corporation ofof Medical Science Traditional Medical School of Tehran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Inclusion criterias:xerostomia at least grade 2 based on Avraham Eisbruch trial's grading(grade1:no malfunction, grade 2:need to exess fluid to swallow, grade 3: changes in nutririon ,sleep,speech and other activities); taking more than 40gray radition to head and neck to be more than three major salivary glands in the radition field;age of 18 years and older; at least 3 mounths later than the end of the radation.
Exclusion criteria:alcohol and other drugs consumption that affect salivary glands like anti depressant;history of connective tissue and collagen vascular diseases like sjogren, rheumatoid arthritis, lupus;systemic or local reccurents;need to prenteralnutrition hospitalsation.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Saliva amount. Timepoint: 3times in 3 mountes intervals. Method of measurement: collecting saliva in 5 mintusein the 1 scaled test tube.;Quality of life. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare.
- Secondary Outcome Measures
Name Time Method Constipation. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare.;Skin dryness. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare.;Quality of sleep. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare.