Non-Invasive Determination of Fetal Chromosome Abnormalities
- Conditions
- Patau Syndrome (Trisomy 13)Down Syndrome (Trisomy 21)Edward's Syndrome (Trisomy 18)Klinefelter Syndrome (47, XXY)and Other ChromosomeAbnormalities.
- Registration Number
- NCT00891852
- Lead Sponsor
- Lenetix Medical Screening Laboratory
- Brief Summary
The overall significance of this study is to develop a laboratory developed test (LDT) to use a new marker in the maternal blood to better identify pregnancies that have a child with a chromosome abnormality such as Down syndrome (trisomy 21), Edward's syndrome (trisomy 18), Patau syndrome (trisomy 13), Klinefelter syndrome, (47, XXY), and other chromosome abnormalities. Accomplishing that task would reduce the need for invasive amniocentesis and CVS procedures.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 1000
- This study is only applicable to women who are between 8 and 30 weeks' gestation and who have been determined increased risk for fetal aneuploidy. In the interest of expediting and simplifying this study, the investigators want only women who have already decided to undergo second-trimester amniocentesis or CVS.
- The only exclusion criteria are those mentioned.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (7)
Maryland Perinatal Associates
🇺🇸Rockville, Maryland, United States
Atlantic Maternal Fetal Medicine
🇺🇸Moristown, New Jersey, United States
Winthrop University Hospital
🇺🇸Mineola, New York, United States
Elite Women's Health
🇺🇸New Hyde Park, New York, United States
Columbia University, NewYork-Presbyterian Hospital
🇺🇸New York, New York, United States
New York Perinatal Associates
🇺🇸New York, New York, United States
UVM
🇺🇸Burlington, Vermont, United States
Maryland Perinatal Associates🇺🇸Rockville, Maryland, United States