The Effect of Concurrent Transcranial Direct Current Stimulation and Gait Training on Gait Performance When Doing the Cognitive Dual-task in People With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 主要终点
- Dual-task walking performance
研究概览
简要总结
To investigate the effect of concurrent transcranial direct current stimulation and gait training on gait performance when doing the cognitive dual-task in people with Parkinson's Disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with idiopathic PD
- •Hoehn and Yahr stages I-III
- •Mini Mental Status Examination (MMSE) score ≧ 24
- •Could walk 10m independently with or without gait aid
排除标准
- •Concurrent medication likely to affect mental performance
- •tDCS contraindication
- •Significant neurological, vestibular, visual disorders or psychiatric illness
- •Musculoskeletal or cardiopulmonary disease
- •Sensory system pathology
研究组 & 干预措施
Active tDCS plus gait training group
Participants in Active tDCS plus gait training group will execute Active tDCS on left dorsolateral prefrontal cortex which combined with treadmill, 12 times per week, least 4 weeks.
干预措施: Active tDCS plus gait training (Other)
Sham tDCS plus gait training group
Participants in Sham tDCS plus gait training group will executeSham tDCS on left dorsolateral prefrontal cortex which combined with treadmill, 12 times per week, least 4 weeks.
干预措施: Sham tDCS plus gait training (Other)
结局指标
主要结局
Dual-task walking performance
时间窗: Change from baseline at 4 weeks
To evaluate gait parameters while doing dual-task walking
次要结局
- Single walking performance(Change from baseline at 4 weeks)
- Digit span test(Change from baseline at 4 weeks)
- Stroop color and word test-Chinese version(Change from baseline at 4 weeks)
- Trail-making test A & B(Change from baseline at 4 weeks)
研究者
Yea-Ru Yang
Professor
National Yang Ming Chiao Tung University