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临床试验/CTRI/2025/09/094064
CTRI/2025/09/094064尚未招募2 期

Evaluation of efficacy and safety of Unani Formulations in management Of Intithar al Shar (Chronic Telogen Effluvium) in healthy females.

Hakim Syed Ziaul Hasan Government Unani Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2025年9月15日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
44
试验地点
1
主要终点
1.Patient Self Assessment

研究概览

简要总结

Hair fall is a common cosmetic concern affecting about 1.7 percent of the global population often leading to psychological distress and reduced quality of life. The major types of hair loss include  telogen effluvium alopecia areata and androgenetic alopecia with varying prevalence worldwide and in India. Telogen effluvium one of the most frequent causes arises from a shortened anagen phase triggered by physiological or psychological stress. It occurs in acute and chronic forms and latter affecting mainly middle aged women without noticeable thinning but with decreased hair volume and length and often idiopathic in origin. The normal hair cycle consists of anagen 3 to 5 years catagen 2 to 3 weeks and telogen 3 to 4 months with daily shedding of up to 100 hairs considered normal but excessive shedding beyond this limit characterizes telogen effluvium. In Unani medicine hair loss Intithar al  shar is attributed to nutritional deficiencies impaired production of bukharat i dukhaniyya skin laxity morbid matter accumulation or fibrosis. Management includes drugs with properties such as Tadil e Mizaj (temperament correction) Taghziya (nutritional support) muqawwi e dimagh  (brain tonic) and Munbit e shar  (hair growth promotion). These formulations are considered safe with no adverse effects reported in classical literature .In contrast  modern medicine provides pharmacological and surgical options such as minoxidil  finasteride nutritional supplements  and low-level light therapy. However these require continuous use may have limited efficacy and are associated with adverse effects. Considering the safety and efficacy described in traditional texts the present study is designed to evaluate Unani polyherbal formulations in the management of chronic telogen effluvium in healthy females.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 45.00 Year(s)(—)
性别
Female

入选标准

  • 1.Clinically diagnosed patient of chronic telogen effluvium.
  • 2.Patients having natural hair colour.
  • 3.Patient who will give written consent and able to do follow up.

排除标准

  • 1.Pregnant women and nursing mothers.
  • 2.Previous hair growth procedure within 3 months.
  • 3.Patient suffering from local infection of the scalp allergic reactions active seborrhic dermatitis.
  • 4.Patient suffering from chronic illnesses like diabetes mellitus thyroid disorders kidney and liver dysfunctions carcinoma tuberculosis.
  • 5.Patients who used topical minoxidil within 6 months prior to enrolment.
  • 6.Patients with surgical correction of scalp hair loss hair transplant or scalp reduction.

结局指标

主要结局

1.Patient Self Assessment

时间窗: Baseline 28th day 56th day

2.Hair comb test 3.Hair pull test

时间窗: Baseline 28th day 56th day

次要结局

  • Quality of life questionnaire(Baseline 56th day)

研究者

发起方
Hakim Syed Ziaul Hasan Government Unani Medical College and Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Mehrun Nisa

Hakim Syed Ziaul Hasan Government Unani Medical College and Hospital

研究点 (1)

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