Evaluation of the Effect of 980nm Diode Laser Intracanal Irradiation on Postoperative Pain and Root Canal Disinfection in Endodontic Retreatment Cases With Chronic Periapical Lesions
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 主要终点
- postoperative pain, measured using Visual analogue scale (VAS)
研究概览
简要总结
A randomized clinical trial that evaluates the effect of using 980nm diode laser intracanal irradiation on postoperative pain and root canal disinfection in endodontic retreatment cases with chronic periapical lesions
详细描述
The endodontic retreatment procedures will be carried out for the participants, then 980nm Diode laser will be used to disinfect root canals. The researcher will then take microbiological samples of the root canals, to determine count and type of microorganisms in root canals. The subject will be asked to determine his level of pain at 7 days after endodontic retreatment procedures in a visual analogue scale (VAS), and to determine number of analgesic tablets needed to relieve his pain in the given charts. The subject will then return to the clinic 7 days later to bring back his charts. The researcher then will take another microbiological sample of the root canals, and complete the endodontic retreatment procedures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
盲法说明
All the participants will be blinded, as they will not know which interventional group they belong to
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Endodontic retreatment cases of single rooted teeth with chronic periapical lesions; with periapical radiolucency of less than 1 cm diameter will be selected.
- •Teeth with straight root canals.
- •Subjects aged between 18-50 years of age.
- •No contributory medical history.
- •No previous administration of analgesics and / or antibiotics within the previous 2 weeks.
排除标准
- •Retreatment cases with complications such as separated instruments, perforations, ledges, resorption, transportation, calcifications, immature apices and over fillings.
- •Teeth with curved roots.
- •Swelling or sinus tract.
- •Mutilated teeth that interfere with proper isolation and seal between visits.
- •Subjects with generalized periodontitis, or if the tooth has probing depth of more than 3 mm.
- •Subjects with uncontrolled diabetes or debilitating diseases.
- •Pregnant or nursing females.
- •Systemic disorders that necessitate antibiotic prophylaxis or prevent the use of Ibuprofen.
研究组 & 干预措施
laser
980 nm diode laser (maximum output of 3 watts and coupled with a fiber optic tip of 200 µm diameter) will be used for four irradiations, of 5 seconds each, after chemo-mechanical preparation procedures.
干预措施: 980 nm diode laser (Radiation)
Placebo
After chemo-mechanical preparation procedures, the diode laser fiber optic tip will be inserted inside the root canals but not activated.
干预措施: placebo (Other)
结局指标
主要结局
postoperative pain, measured using Visual analogue scale (VAS)
时间窗: 7 days after root canal re-treatment procedures
Visual analogue scale (VAS) will be used for to record severity of pain. It is a (0-10) scale. Criteria to determine the severity of postoperative pain will be as follows: (0: no pain), (1-3: mild pain), (4-6: moderate pain), (7-10: severe pain).
次要结局
- Root canal disinfection(Four samples will be taken; first, second and third samples will be taken at first visit of endodontic retreatment procedures. while, the fourth sample will be taken in the second visit (7 days later).)
- number of analgesic tablets(At day 7 after endodontic retreatment procedures)
研究者
Eman Nabil El-Ezaby
Principal investigator
Cairo University