NCT07328178招募中不适用
Analysis of the Role of IgE Proteoforms in Health and Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- KU Leuven
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Evaluation of IgE proteoforms
研究概览
简要总结
The goal of this observational study is to evaluate the role of IgE proteoforms in healthy volunteers and in patients with type I allergy, patients with chronic spontaneous urticaria, patients with a recent history of anaphylaxis, patients with mastocytosis, patients with hereditary alpha tryptasemia, patients with X-linked agammaglobulinemia (XLA), and patients undergoing desensitization for venom or medication allergy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •CSU and type I allergic diseases (including anaphylaxis and desensitization), atopic dermatitis, mastocytosis, XLA and HaT (informed consent, age: any available adult subject, gender: any available subject, clinical phenotype and specific information about the allergy (e.g. severity, medication, medical history, laboratory testing)
- •Healthy controls (informed consent, age matched to the allergic patients, gender matched to the allergic patients, patient-reported symptoms related to allergy to aeroallergens, food, drugs, hymenoptera venom, CSU)
排除标准
- •Absence of informed consent
- •Age < 18 years old
结局指标
主要结局
Evaluation of IgE proteoforms
时间窗: 4 years
次要结局
未报告次要终点
研究者
Rik Schrijvers
Prof. Dr. Rik Schrijvers
Universitaire Ziekenhuizen KU Leuven
研究点 (1)
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