Pilot Study of Hippocampal Function in Type 1 Diabetes Mellitus (T1DM)

Completed

• Conditions: Type 1 Diabetes Mellitus

• Registration Number: NCT00918801
• Lead Sponsor: Washington University School of Medicine

Brief Summary

This study is an expansion of a previous study done to determine how thinking skills relate to hypoglycemia (low blood sugar) and certain regions of the brain in children and adolescents. In this study, the investigators are testing thinking skills and measuring brain activity in adolescents with and without type 1 diabetes mellitus.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04
• Study First Submitted: 2009-06-08
• Study First Submitted QC: 2009-06-09
• Study First Posted: 2009-06-11
• Primary Completion: 2013-12
• Study Completion: 2016-10
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-09
• Last Update Posted: 2016-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

• Age 13 - 18
• Right handed
• Diagnosis of Type 1 Diabetes OR normal sibling control
• If diabetic, then diagnosis for at least 2 years

Exclusion Criteria

• Pregnant or lactating
• Chronic disease other than well-controlled asthma, or Hashimoto's thyroiditis.
• Other current serious medical illness
• Co-morbid psychiatric illness
• Co-morbid neurological illness
• Pre-maturity at birth
• Contraindication to MRI scan
• orthodontic braces.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Washington University School of Medicine; 🇺🇸 St. Louis, Missouri, United States