THERAPEUTIC EVALUATION OF RASNADI GUTIKA AND CHANDRAKALA LEPA IN JANU SANDHIGATA VATA(OSTEO ARTHRITIS KNEE)

CENTRAL COUNCIL FOR RESEARCH IN AYURVEDIC SCIENCES JANAKPURI NEW DELHI0 个研究点目标入组 120 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1)Patients of either sex aged between 40 and 75 years.
•2)Patient with primary osteoarthritis Knee joint(s) fulfilling the diagnostic criteria of osteoarthritis recommended by the American College of Rheumatology; i.e. Knee pain and; At least three of the following 6 criteria: 50 years of age or older, stiffness lasting less than 30 minutes, crepitus, bony tenderness, bony enlargement, no warmth to the touch
•3)Pain in the affected Knee joint(s) > 3 months (with radiological changes as per Grade I to III of Kellgren & Lawrence Radiological scale) i.e.
•Grade 1: Narrowing is defined as doubtful narrowing of joint space and possible osteophytic
•Grade 2: Osteophytes and definite narrowing of joint space.
•Grade 3: Moderate multiple osteophytes, definite narrowing of joint space, some sclerosis and
•possible deformity of bone ends.
•4)Willing and able to participate in the study for 03 months.

•1.Patients with Grade IV Kellgren & Lawrence Radiological scale i.e.
•Grade 4: Large osteophytes, marked narrowing of joint space, severe sclerosis and definite deformity of bone contour.
•2.History of any trauma/ fractured joint / surgical/diagnostic intervention with reference to the affected joint(s).
•3.Gross disability in performing daily normal routine i.e. bed ridden patients or confined to a wheelchair.
•4.Patients with co morbidities such as gouty arthritis, rheumatoid arthritis and psoriatic arthritis.
•5.Patients having any deformity of knee hip or back altering the gait and posture of the patient.
•6.Patients with Unstable cardiovascular diseases.
•7.Patients with uncontrolled diabetes mellitus {HbA1c >6.5%}.
•8.Patients with evidence of malignancy.
•9.Patients on prolonged ( > 6 weeks) medication with corticosteroids, antidepressants, anticholinergics, etc. or any other drugs that may have an influence on the outcome of the study.
•10.Patients with any severe renal or hepatic or any other disorder which may interfere in the study.
•11.Pregnant / lactating woman.
•12.Patients who have participated in other clinical trials within two months of duration.
•13.Any other condition which the Principal Investigator thinks may jeopardize the study.

发起方

CENTRAL COUNCIL FOR RESEARCH IN AYURVEDIC SCIENCES JANAKPURI NEW DELHI