Improve Hip Fracture Outcome In The Elderly Patient (iHOPE): a multicentre randomized controlled trial to test the efficacy of spinal versus general anaesthesia

Not Applicable

• Conditions: S70-S79; Injuries to the hip and thigh

• Registration Number: DRKS00013644
• Lead Sponsor: Klinik für Anästhesiologie, Uniklinik RWTH Aachen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-04-10
• Study Completion: 2023-08-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 770

Inclusion Criteria

Age = 65 years; signed informed consent; suffers from intra-/extracapsular hip fracture (e.g. femoral neck fracture, subtrochanteric or intertrochanteric fracture), planned surgical treatment via hemiarthroplasty, total hip arthroplasty or appropriate osteosynthetic procedure

Exclusion Criteria

People who are institutionalized by court or administrative order;
planned concurrent surgery not amenable to spinal anaesthesia;
absolute contraindications to spinal anaesthesia; periprosthetic
fracture; prior participation in the iHOPE study; as determined by the
attending surgeon, the attending anaesthesiologist, or the site
principle investigator or their designate, that the patient or the
attending team would not be suitable for a randomization procedure

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To test Efficacy of spinal versus general anaesthesia on allcause mortality and new-onset (i.e. not pre-existing at time of surgery) serious cardiac and pulmonary complications up to 30-days after hip fracture surgery.