Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor

Recruiting

• Conditions: Cesarean Section; Epidural; Anesthesia

• Registration Number: NCT04074005
• Lead Sponsor: Mahidol University

Brief Summary

The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia. Besides, factors associated with the rate of cesarean delivery were studied.

Detailed Description

Epidural analgesia with local anesthetic and opioid is the efficiently good method to relieve labor pain comparing with intravenous opioid analgesic. Many literatures reported effects epidural analgesia for labor eg. prolonging the duration of second stage of labor, increasing the rate of instrumental delivery: vacuum extraction and forceps assisting labor. Some papers revealed the increasing in the rate of cesarean delivery. The main reason is assume to be a failure to progress labor after epidural analgesia. However, the recent report from Cochrane database systematic review showed no relation of epidural analgesia for labor and the increasing in the rate of cesarean delivery. Various factors that may involve in the increasing in the rate of cesarean delivery including the dilatation of cervix at the time of insertion of epidural catheter, nulliparous, size of the fetus or motor weakness after receiving epidural medication.

The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia. Besides, factors associated with the rate of cesarean delivery were studied.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2019-05-04
• Study First Submitted QC: 2019-08-28
• Study First Posted: 2019-08-29
• Study Start: 2019-09-01
• Status Verified: 2024-03
• Last Update Submitted: 2024-03-18
• Last Update Posted: 2024-03-19
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 226

Inclusion Criteria

• Age>,= 18 years
• Accept epidural analgesia for labor
• ASA classification I-II

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Exclusion Criteria

• Unable to communicate Thai

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of cesarean delivery after epidural analgesia for labor	From epidural catheter insertion to delivery	Rate of cesarean delivery after patients receive epidural analgesia for relieve labor pain

Secondary Outcome Measures

Name	Time	Method
Side effects of epidural analgesia for labor: nausea and vomiting	From epidural catheter insertion to delivery	nausea and vomiting (rating by patients: 0= no symptom, 1= nausea 2= vomiting)
Side effects of epidural analgesia for labor: numbness of legs	From epidural catheter insertion to delivery	numbness of legs (0=no, 1=yes)
Side effects of epidural analgesia for labor: pruritus	From epidural catheter insertion to delivery	pruritus (0=no, 1=yes)
Side effects of epidural analgesia for labor: motor weakness	From epidural catheter insertion to delivery	Rate motor weakness by Bromage score
Factors affecting rate of cesarean delivery after epidural analgesia for labor	at the time epidural catheter insertion	cervical dilatation before insertion epidural catheter (cm.)
Efficacy of epidural analgesia for labor	before and after epidural catheter insertion	pain score (verbal rating scale pain score)

Trial Locations

Locations (1)

Siriraj Hospital, Mahidol University; 🇹🇭 Bangkok, Thailand