MRI analysis of the spread of local anaesthetic following ultrasound guided lateral paravertebral blockade: a volunteer stduy
- Conditions
- healthy volunteers
- Registration Number
- DRKS00003323
- Lead Sponsor
- niversitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 10
•Healthy males aged between 18 and 45 years
•BMI < 30 kg/m2
•Written informed consent given by volunteers after being provided with detailed information about the nature, risks, and scope of the clinical study as well as the expected desirable and adverse effects of the drug
•No legal incapacity and/or other circumstances rendering the subject unable to understand the nature, scope and possible consequences of the study
•Anatomical abnormalities of the thoracic spine identified by physical examination
•Spontaneous pneumothorax in the medical history
•BMI =31 kg/m2
•Claustrophobia
•Use of NSAID during the last 2 weeks
•Known allergy or hypersensitivity against mepivacaine or amino-amide local anaesthetics
•Participation in another clinical study within the last 4 weeks prior to study
•Coagulopathy
•Abnormalities in ECG that are considered clinically relevant like AV-block or bradykardia
•Unreliability and/or lack of cooperation
•Other objections to participate in the study in the opinion of the investigator
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MRI visulizied evaluation of spread of local anaesthetics after ultrasound guided paravertebral block
- Secondary Outcome Measures
Name Time Method pharmacodynamic of paravertbral block