A Study of the Physical Health and Genetics of Post-Traumatic Stress Disorder (PTSD).

Not Applicable

Completed

• Conditions: Post-Traumatic Stress Disorder; Mental Health - Other mental health disorders

• Registration Number: ACTRN12614000429651
• Lead Sponsor: Returned Services League (RSL) Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-04-17
• Study Completion: 2015-07-22
• Last Update Posted: 27 December 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 311

Inclusion Criteria

1. Australian males who served as members of the Australian Defence Force in Vietnam during the Vietnam War (irrespective of potential diagnosis of PTSD, or lack thereof).
2. Participants must have read and signed the Participant Information Sheet and signed the Informed Consent Form (PISICF).
3. Participants must be willing to attend GMRF-GPH for all appointments.
4. Participants must be willing to undergo medical and psychological history and clinical examination and test procedures as outlined in the PISICF.
5. Participants must reside sufficiently close to GPH to attend for the required study assessments.

Exclusion Criteria

1. Previous diagnosis of schizophrenia or bipolar disorder

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinician-Administered PTSD Scale (CAPS)[Following informed consent.]

Secondary Outcome Measures

Name	Time	Method
Coronary Artery Calcium (CAC) Score.[Within 6 weeks of informed consent.];Blood albumin level (g/L)[Within 6 weeks of informed consent.];Liver FibroScan score[Within 6 weeks of informed consent.];The G allele of single nucleotide polymorphism (SNP) rs386231 in the nitric oxide synthase1 adaptor protein (NOS1AP) gene.[Within 6 weeks of informed consent.]