Prenatal Examination of Deletion 22q11 Syndrome : Thymic Dysgenesis THYMI Study
Completed
- Conditions
- 22q11 Deletion Syndrome Di George Syndrome
- Registration Number
- NCT02890472
- Lead Sponsor
- Centre Hospitalier Universitaire de Nīmes
- Brief Summary
22q11.2 microdeletion seems the prenatally under-diagnosed . Indeed , there is a mismatch between the series on the heart rate of 22q11.2 antenatal 84% against 30% in the adult series despite a perinatal mortality of 16% suggesting opportunities for improvement in the prenatal diagnosis of fetus with a microdeletion 22q11.2 , especially without heart disease
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 13
Inclusion Criteria
- all prenatal diagnosis with FISH or CGH array of a fetal 22q11 deletion syndrome during the inclusion period.
- The pregnancy follow-up should be done one of the 44 french fetal medicine unit.
- Sonographic picture of 3 vessels slides should be communicated for independent review.
Exclusion Criteria
- no sonographic picture available
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Thymic thoracic ratio " measurement on sonographic picture of the fetal 3 vessels slides will be done by independent investigator. day 0
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHUNimes
🇫🇷Nîmes, France