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Clinical Trials/NCT01430897
NCT01430897
Completed
Not Applicable

Right Ventricular Hypertrophy After Atrial Switch Operation and Its Role in a Systemic RV: Normal Adaptation Process or Risk Factor? A Cardiovascular Magnetic Resonance Study

University of Leipzig1 site in 1 country37 target enrollmentStarted: April 2007Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
University of Leipzig
Enrollment
37
Locations
1

Overview

Brief Summary

Systemic RV hypertrophy and impaired systolic function occur after atrial switch (AS) in d-transposition of the great arteries (d-TGA). Echocardiography has limitation in the assessment of the right ventricle (RV).

In this study the investigators sought to evaluate systemic RV myocardial mass and function after AS for d-TGA and to analyze the role of excessive hypertrophy for ventricular function under special consideration of the interventricular septal (IVS) movement.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Eligibility criteria were an AS operation in childhood for correction of d-TGA and the absence of associated hemodynamically significant heart defects.

Exclusion Criteria

  • Exclusion criteria were usual CMR contraindications such as ferromagnetic metallic implants.

Investigators

Sponsor
University of Leipzig
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Matthias Grothoff, M.D.

Consultant Radiology

University of Leipzig

Study Sites (1)

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