Impact of intravenous iron injections on musculoskeletal function in older adults

Phase 4

• Conditions: Iron deficiency anaemia; Circulatory System

• Registration Number: ISRCTN13325706
• Lead Sponsor: iverpool Hope University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-01-28
• Last Update Posted: 18 March 2024
• Study Completion: 2026-06-01

Recruitment & Eligibility

• Status: Stopped
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Anaemia attributable to iron deficiency
2. Haemoglobin <120 g/L in women, Hb <130 g/L in men
3. Ferritin <=100 ng/mL or <=300 ng/mL if transferrin saturation (TSAT) <=30%
4. Age >=60 to 85 years
5. Ambulatory individuals
6. BMI <=40 kg/m²
7. Written informed consent

Exclusion Criteria

1. Uncontrolled hypertension/ diabetes
2. Potential medication interactions
3. Hemochromatosis or iron storage disorders
4. Recent treatment with IV antibiotics or red blood cell transfusion
5. Dialysis dependent
6. History of malignancy
7. Pregnant or lactating women
8. Severe hepatic and renal dysfunction
9. Advanced cardiovascular disease and COPD
10. Advanced Neuromuscular disorder
11. Obvious cognitive disability and psychological illness
12. Current treatment with systemic steroids or any other substantive medication
13. Alcohol or any other drug abuse

Study & Design

• Study Type: Interventional
• Study Design: Not specified