Substance Use in Assault-Injured Young Adults

Not Applicable

Not yet recruiting

• Conditions: Alcohol Misuse; Cannabis Misuse

• Registration Number: NCT07070414
• Lead Sponsor: Yale University

Brief Summary

This study aims to improve a short motivational conversation to better help young adults who were injured in assaults and also use alcohol or cannabis. Researchers will gather both interview and survey data from young adults who came to the emergency department after an assault and currently use alcohol or cannabis. Guided by a theory about risky behaviors, the study will focus on how confident young people feel about making changes to their alcohol and cannabis use, and how their friends and family influence their alcohol and cannabis use and involvement in injuries from assault. The team will follow a step-by-step process used by the NIH to adapt and test the improved motivational conversation in the emergency department.

Detailed Description

Aim 1: Quantitatively and qualitatively assess self-efficacy, perceived peer and familial norms, and motivation to reduce alcohol and/or cannabis use and engage in treatment referral, among assault-injured emerging adults. AIM 2: Adapt the BNI for use among assault-injured emerging adults with alcohol and/or cannabis misuse in the ED. AIM 3: Determine the feasibility and acceptability of an adapted BNI among assault-injured emerging adults with alcohol and/or cannabis misuse presenting to the ED through a randomized pilot trial comparing those who have received the adapted BNI and treatment referrals to a referrals-only control group. The focus of this registration is the randomized pilot in Aim 3.

Study Timeline

• Status Verified: 2025-07
• Study First Submitted: 2025-07-08
• Study First Submitted QC: 2025-07-08
• Last Update Submitted: 2025-07-08
• Study First Posted: 2025-07-17
• Last Update Posted: 2025-07-17
• Study Start: 2025-09-01
• Primary Completion: 2028-02
• Study Completion: 2028-02-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Aim 1:

• Be clients of the Yale Hospital Violence Intervention Program (YHVIP)
• Be between the ages of 18-25 y/o upon study enrollment
• Have sustained an intentional injury inflicted by another person not considered to be a boy/girlfriend, fiancée, or spouse in the past year
• Report current alcohol and/or cannabis misuse
• Be English-speaking and able to provide informed consent.

Aim 2 and 3:

• Present to Yale New Haven Hospital ED for an intentional injury inflicted by another person not considered to be a boy/girlfriend, fiancée, or spouse
• Be between the ages of 18-25 y/o upon study enrollment
• Report current alcohol and/or cannabis misuse
• Be English-speaking and able to provide informed consent.

Exclusion Criteria

Aim 1:

• Be actively suicidal or severely cognitively impaired precluding informed consent
• Sustain an intentional injury from a boy/girlfriend, fiancée, or spouse or sexual assault
• Be incarcerated or in police custody
• Currently engaged in addiction treatment

Aim 2 and 3:

• Be actively suicidal or severely cognitively impaired precluding informed consent
• Sustain intentional injury from a boy/girlfriend, fiancée, spouse or by sexual assault
• Be incarcerated or in police custody
• Currently engaged in addiction treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Feasibility assessed by recruitment	Day 0 and 30	Recruitment measured as the percentage of those invited/those who enrolled
Feasibility assessed by randomization	Day 0 and 30	Recruitment measured as the percentage of screened eligible participants who enroll/those who receive either intervention or control arm
Feasibility assessed by retention	Day 0 and 30	Recruitment measured as the percentage of those enrolled who have received either intervention or control arm/ participants who have completed all 30-day follow up assessments
Acceptability assessed by Acceptability of Intervention Measure (AIM)	Day 0	Acceptability of the intervention will be assessed using the Acceptability of Intervention Measure (AIM). It has 4-items scored on a 5-point Likert scale summed to achieve a total score. Total score range of 0-20. Higher scores indicate more acceptability.

Trial Locations

Locations (1)

Yale Department of Emergency Medicine; 🇺🇸 New Haven, Connecticut, United States