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Clinical Trials/NCT04358250
NCT04358250
Completed
N/A

Tissue Sparing Surgery in Total Hip Arthroplasty

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio2 sites in 1 country50 target enrollmentApril 26, 2017

Overview

Phase
N/A
Intervention
Not specified
Conditions
Total Hip Arthroplasty
Sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Enrollment
50
Locations
2
Primary Endpoint
evaluate spatiotemporal variables in meters among two different access routes, one a traditional posterolateral mini approach and the other a modified posterolateral superior approach fascia lata sparing
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Rationale of the study is to evaluate through a prospective randomized controlled study if a modified direct superior posterolateral approach (sperimental approach) to the hip articulation which entirely spares i.e. avoids the sacrifice of the fascia lata might elicit a better outcome in terms of gait, balance, strengths recovery, clinical performance, patient reported outcome measurement (Short Form-12(SF-12); Hip disability and Osteoarthritis Outcome Score (HOOS)) and overall recovery time in patients undergoing TotalHipArthroplasty with the aid of dedicated, modified instrumentation in order to properly access this modified route.

The investigators expect an improvement on selected gait analysis parameters in sperimental approach in order of 2% of range of motion (ROM) recorded 1 month after surgery. Based on this assumption sample size calculation will be conducted.

Detailed Description

Rationale of the study is to evaluate through a prospective randomized controlled study if a modified direct superior approach (experimental approach) to the hip articulation which entirely spares i.e. avoids the sacrifice of the fascia lata (posterolateral approach) might elicit a better outcome in terms of gait, balance,strenghts recovery, clinical performance, patient reported outcome measurements and overall recovery time in patients undergoing TotalHipArthroplasty with the aid of dedicated, modified instrumentation in order to properly access this modified route.Two patients groups will randomly be allocated in one of the two group with a computer generated 1:1 randomization table.Total number of subjects participating in the study:50.

Registry
clinicaltrials.gov
Start Date
April 26, 2017
End Date
November 30, 2018
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients affected by:
  • Non-inflammatory degenerative joint disease, including osteoarthritis
  • Patients in the age from 60 to 85 included
  • Consenting to actively participate in the study and in the rehabilitation follow up program as foreseen by the study
  • 18 ≤ Body Mass Index (BMI) ≥ 30 kg/m2
  • patient without contralateral THA

Exclusion Criteria

  • Revision procedures where other treatments or devices have failed
  • Active infection or suspected latent infection in or about the hip joint
  • Bone stock that is inadequate for support or fixation of the prosthesis
  • skeletal immaturity
  • any mental or neuromuscular disorder that would create an unacceptable risk of prosthesis instability, prosthesis fixation failure or complication in post-operative care
  • Obesity (BMI ≥30kg/m2)

Outcomes

Primary Outcomes

evaluate spatiotemporal variables in meters among two different access routes, one a traditional posterolateral mini approach and the other a modified posterolateral superior approach fascia lata sparing

Time Frame: Change from Baseline spatiotemporal variables in meters at 3 months

spatiotemporal variables: step length (meters), stride length (meters).

evaluate spatiotemporal variables in percentage among two different access routes, one a traditional posterolateral mini approach and the other a modified posterolateral superior approach fascia lata sparing

Time Frame: Change from Baseline spatiotemporal variables in percentage at 3 months

Spatiotemporal variables: stance phase (percentage), swing phase (percentage)

evaluate kinematic parameters in degrees among two different access routes, one a traditional posterolateral mini approach and the other a modified posterolateral superior approach fascia lata sparing

Time Frame: Change from Baseline Kinematic parameters in degrees at 3 months

Kinematic parameters (in degrees): hip flexion-extension ROM, hip abduction-adduction ROM, Hip rotation ROM, Hip Obliquity ROM.

Secondary Outcomes

  • evaluation of instability with BEStest(Change from Baseline BESTest at 3 months)

Study Sites (2)

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