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Effects of marine healing on menopausal symptoms, bone biomarkers, and intestinal microbial community in postmenopausal wome

Not Applicable
Not yet recruiting
Conditions
Diseases of The genitoruinary system
Registration Number
KCT0004025
Lead Sponsor
Chonnam National University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not yet recruiting
Sex
Female
Target Recruitment
60
Inclusion Criteria

Healthy menopausal women under the age of 65 with menopausal symptoms
habitually low Ca intake (< 600 mg/d)
no avoidance to seaweeds and are willing to comply to the controlled feeding
who can consume food intake as usual in about 2 weeks immediately before marine healing program in Wando
females able to stay in the housing provided for the marine healing program
who will not take or administration antibiotics within six months of the start of the marine healing program

Exclusion Criteria

A person without menopausal symptoms
Habitual Ca intake above 600 mg/d
taking medications related to calcium metabolism or have a disease affecting calcium metabolism
have had a fracture in during the past 6 months
have severe digestive system disease
taking / administering hormones or steroids
have liver, kidney, or thyroid disease
smokers

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
biomarkers related to calcium metabolism (serum Ca, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, parathyroid hormone, phosphorus)
Secondary Outcome Measures
NameTimeMethod
gut microbiome;Menopause Rating Scale (MRS);Validity of 24 hour recalls
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