Assessment of the effects of topical sodium cromoglicate on itch and flare in human skin

Completed

• Conditions: Itch and flare in human skin; Signs and Symptoms; Itch and flare

• Registration Number: ISRCTN35671014
• Lead Sponsor: Hewlett Healthcare Ltd (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-09-21
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Healthy adult volunteers (18 - 65 years old), male only
2. Recruited from the staff and students of Southampton University Medical School and Southampton General Hospital

Exclusion Criteria

1. Pregnancy
2. Presence of skin disease
3. Taking of drugs which may interfere with the study, including corticosteroids, antihistamines, antidepressants and psychotropic drugs

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Change in severity of itch measured every 20 seconds for 5 minutes after injection of histamine using 100 mm Visual Analogue Scale<br> 2. Change in area of flare and blood flux using scanning laser Doppler imaging<br>3. Change in area of weal using planimetry

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures