NCT01463969已完成不适用
High Plasma Level of Long Pentraxin 3 is Associated With Insulin Resistance in Women With Polycystic Ovary Syndrome
Gulhane School of Medicine3 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2010年5月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 3
- 主要终点
- Level of of pentraxin3 in cases with Polycystic Ovarian Syndrome
研究概览
简要总结
In the present study, serum pentraxin 3 level and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS. It was found that PTX3 level is increased in patients with PCOS and it is positively correlated with HOMA-IR.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Absence of significant abnormalities on physical examination except hirsutism
- •No lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
- •Normal thyroid function and prolactin level
- •Absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease
排除标准
- •Possible ovarian tumors,
- •Congenital adrenal hyperplasia or
- •BMI greater than 35 kg/m2
结局指标
主要结局
Level of of pentraxin3 in cases with Polycystic Ovarian Syndrome
时间窗: 1 year
Mean PTX3 was significantly higher in patients with PCOS. This means that there is increased level of inflamation in patients with PCOS.
次要结局
- Relationship of PTX3 with insuline resistance in patients with PCOS.(1 year)
研究者
Aydogan Aydogdu
MD
Gulhane School of Medicine
研究点 (3)
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