COMPARATIVE EVALUATION OF EFFECT OF SCALING AND ROOT PLANING ALONE AND GREEN COFFEE BEAN EXTRACT GEL AS AN ADJUNCT TO SCALING AND ROOT PLANING ON TOTAL ANTIOXIDANT CAPACITY IN PATIENTS WITH STAGE â…¡ PERIODONTITIS- CLINICO BIOCHEMICAL STUDY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Evaluate the Total antioxidant capacity efficacy of green coffee bean extract gel as an adjunct to Scaling and Root Planing in Stage II periodontitis patients
研究概览
简要总结
This study is designed to be a split mouth single blinded randomized control trial where 15 patients of both the gender with Stage II periodontitis (accordance with the guidelines established during the World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions - stage II) with probing pocket depth equal to or lesser than 5 mm in atleast 2 quadrant . The total sample size calculated is 15 patients. This will be a split mouth study where the oral cavity is divided into right and left quadrant. One quadrant will be treated by scaling and root planing alone, and counterpart quadrant with scaling and root planing with green coffee bean extract gel application. The quadrant will be selected using computerized randomization method. Thereby a total of 30 sites will be included in the study. All clinical parameters will be measured and GCF collection will be done at baseline, 1 month and 3 month after scaling and root planing and gel application will be done at baseline. Full mouth scaling and root planing and gel application will be performed at baseline following initial examination. Therefore, this study is an attempt to evaluate the total antioxidant capacity efficacy of green coffee bean etract gel as an adjunct to scaling and root planing in stage II periodontitis patients among patients attending outpatient department of Coorg institute of dental sciences ,Virajpet for treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 55.00 Year(s)(—)
- 性别
- All
入选标准
- •Subjects who are diagnosed with clinical Stage II periodontitis and willing for treatment.Patients 20 to 55 years of age.Patients with periodontal pocket depth greater than or equals to 5mm at least in 2 quadrants.Minimum of 15 teeth should be remaining.
排除标准
- •Systematically compramised patients.use of antibiotics in past 6 months.
- •Steriods or inflammatory drugs for 7 days in 3 months.
- •Known allergy to above mentioned drug or substances.
- •Smokers and alcoholic.
- •Pregnant and lactating women.periodontal therapy within 6 months.
结局指标
主要结局
Evaluate the Total antioxidant capacity efficacy of green coffee bean extract gel as an adjunct to Scaling and Root Planing in Stage II periodontitis patients
时间窗: All clinical parameters will be measured and GCF collection will be done at baseline, 1 month and 3 month after scaling and root planing and gel application will be done at baseline
次要结局
- compare the results of clinical parameters & Total antioxidant capacity levels between scaling & root planing alone & green coffee bean extract gel as an adjunct to Scaling & root planing in the management of Stage II periodontitis(All clinical parameters will be measured & GCF collection will be done at baseline, 1 month & 3 month after scaling & root planing & gel application will be done at baseline)
研究者
LINET V GEORGE
Coorg institute of dental science
