A Multicenter Study to Evaluate the Immediate and Delayed Effects of Individualized Metacognitive Therapy for Psychosis (MCT+)
Not Applicable
- Conditions
- F20Schizophrenia
- Registration Number
- DRKS00008001
- Lead Sponsor
- niversitätsklinikum Hamburg-EppendorfKlinik und Poliklinik für Psychiatrie und Psychotherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 328
Inclusion Criteria
1) schizophrenia or schizoaffective disorder (confirmed by MINI)
2) informed consent
Exclusion Criteria
1) intelligence: IQ < 70 (Wortschatztest)
2) PANSS scores = 5 for hostility and non-cooperativeness (G8, P7);
3) high suicide risk
4) current alcohol or substance dependence, excluding tobacco (abstinence < 6 months; alcohol and substance abuse are allowed)
5) any form of documented or suspected major neurological or general medical condition that might be responsible for the psychotic manifestations
6) participation in MCT+ in the past 12 months
7) insufficient German language abilities
8) insufficient capability for assessment
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The PSYRATS is a commonly used semi-structured interview that measures quantitative and qualitative aspects of delusions and hallucinations, including preoccupation, conviction and distress. The difference in PSYRATS score for both delusions and hallucinations from T0 to T2 serves as the primary outcome parameter. The validity of the PSYRATS has been demonstrated in chronically psychotic patients and it has been shown to have good psychometric properties. Three outcome time points: Baseline, post-assessment (6 weeks after baseline) and follow-up (6 months).
- Secondary Outcome Measures
Name Time Method