The Value of Diaphragmatic Ultrasound in Non-invasive Oxygen Therapy

• Conditions: Diaphragm Ultrasound; Intensive Care Unit

• Registration Number: NCT04355559
• Lead Sponsor: Chinese PLA General Hospital

Brief Summary

In this study, a single-center, prospective, observational study was adopted to set the cut-off values of diaphragmatic ultrasound results and arterial blood gas results，with the choice of non-invasive oxygen therapy as the gold standard,so as to evaluate the diagnostic value of diaphragmatic ultrasound in the selection of non-invasive oxygen therapy.

Detailed Description

1. the cut-off values of diaphragmatic ultrasound results and arterial blood gas results were established by the selection results of non-invasive oxygen therapy of 120 patients in the intensive care unit and using receiver operating Characteristic curve.

diaphragm excursion，inspiratory time，diaphragm contraction velocity，diaphragm excursion time

Study Timeline

• Study Start: 2018-08-01
• Study First Submitted: 2020-03-24
• Status Verified: 2020-04
• Study First Submitted QC: 2020-04-20
• Last Update Submitted: 2020-04-20
• Study First Posted: 2020-04-21
• Last Update Posted: 2020-04-21
• Primary Completion: 2020-04-30
• Study Completion: 2020-08-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• patients older than 18 years
• without Invasive mechanical ventilation when entering the intensive care unit.

Exclusion Criteria

• have noninvasive ventilation or high flow nasal cannula contraindications
• history of neuromuscular disease chest wall deformities
• previously assessed diaphragmatic palsy
• shock or severe hemodynamic instability
• known pregnancy, and/or need for immediate endotracheal intubation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the data diaphragmatic ultrasound	When the intervention which is the first time to change the oxygen therapy	Record the data at the baseline and intervention

Secondary Outcome Measures

Name	Time	Method
Arterial blood gas analysis results	When the intervention which is the first time to change the oxygen therapy	Record the data at the baseline and intervention

Trial Locations

Locations (1)

Department of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital; 🇨🇳 Beijing, Beijing, China