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Clinical Trials/NCT05680987
NCT05680987
Recruiting
Not Applicable

Utilizing the Retrograde Femoral Nail-Advanced for Fixation of Distal Femur and Femoral Shaft Fractures: A Prospective Case Series

University of California, San Diego1 site in 1 country40 target enrollmentJune 23, 2021

Overview

Phase
Not Applicable
Intervention
RFN-Advanced Retrograde Femoral Nailing System
Conditions
Femoral Fracture
Sponsor
University of California, San Diego
Enrollment
40
Locations
1
Primary Endpoint
Healing Rates
Status
Recruiting
Last Updated
2 months ago

Overview

Brief Summary

This project consists of a prospective and retrospective case series design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have a distal femur or femoral shaft fracture requiring surgical fixation. Patients who consent to study participation will recieve the RFN-advanced Retrograde Femoral Nailing System implant for fracture fixation. Data on functional status, healing rates, complication rates, and pain levels will be collected for each participant. After 3 years of data collection, investigators will analyze this data to provide further insight on the utility of this new design of retrograde femoral nails. Given the relatively high rate of complications, such as malalignment, with current femoral nail designs, it is imperative to evaluate novel systems to appropriately manage distal femur or femoral shaft fractures.

Registry
clinicaltrials.gov
Start Date
June 23, 2021
End Date
June 23, 2026
Last Updated
2 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

William Kent

Assistant Professor of Orthopaedic Surgery

University of California, San Diego

Eligibility Criteria

Inclusion Criteria

  • Distal femur or femoral shaft fracture requiring surgery
  • Evaluation and treatment at UCSD
  • Age 18 years or older
  • Ability to understand the content of the patient information/Informed Consent Form
  • Signed and dated IRB-approved written informed consent

Exclusion Criteria

  • Any not medically managed severe systemic disease
  • their doctor has decided that it is in the patient's best interest to receive a different method of fixation
  • Their doctor has determined that the patient has a condition that would make them unsuitable for participation in the study
  • Pregnancy or women planning to conceive within the subject participation period (1 year) note: pregnancy will be self-reported and no test will be performed to test for it
  • Participation in any other pharmacologic or medicinal product study within the previous month that could influence the results of this study

Arms & Interventions

Retrograde Femoral Nail-Advanced

Intervention: RFN-Advanced Retrograde Femoral Nailing System

Outcomes

Primary Outcomes

Healing Rates

Time Frame: 2 years

Secondary Outcomes

  • Pain Score (0-10,0=no pain, 10=most severe)(1 year)
  • Number of Complications(1 year)

Study Sites (1)

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