“To evaluate the effect of Kashyapokta and Vagbhatokta Kala Basti with Panchamoolabalasiddha Ksheera in Janu Sandhigatavata - A Comparative Clinical Studyâ€

In Panchakarma, Basti is considered as “Ardhachikitsa†in the management of disease. When Basti is administered, it reaches pakwashaya and removes dosha from all over the body.It is the best treatmentline for Asthyashrayaja vyadhi.As per Acharya Charaka, Basti is mentioned as Vataharanam shrestam.So it is helpful in vatajadiseases like Janu Sandhigatavatawhere vriddhiin Ruksha guna of vata and kshaya of shleshakakaphaproduces pain and stiffness of knee joint during movement. All Vatavyadhirequires shodhana along with brumhanaline of treatment. Acharya Sushruta has mentioned that 9-11 Anuvasana Basti is required for vata predominant diseases.This is fulfilled by Kala Basti pattern of Acharya Kashyapaand *Acharya Vagbhata.*Janu Sandhigatavata is vatajavyadhipresented with symptoms of *Sandhishoola,vatapurnadrutisparshashothaand prasaranaakunchana vedana.*It has symptoms similar to osteoarthritis of knee in conventional science. OA is age related chronic degenerative disease characterized by deterioration of cartilage of joints that results in bone rubbing together and creating stiffness, pain and impairment in movement.

Osteoarthritis is second most common rheumatological problem with prevalence of 22% to 39% in India. By 2025 India may become the osteoarthritis capital of the world with over 60 million cases. Almost all persons over the age 40 have some bodily transformation in weight bearing joints. And this prevalence of OA is increasing with age and risk factors.The treatment of osteoarthritis mainly focuses on pain management using NSAIDS, Topical Analgesics, corticosteroids injection and lastly joint replacement surgery.  As OA is an inevitable part of ageing, there is no other satisfactory treatment. As long-term intake of oral medication has its own side effects, so to deal with chronic joint diseases Ayurvedic management seems to be the best.

Panchamoolabalasiddha Ksheera is indicated in Vataja vikara. Acharya Charaka mentions that whatever the medicine indicated in particular disease can be used in the form of basti.Panchamoola (laghu panchamoola) contains tikta,madhura rasa pradhana dravyas having vataghna, brumhana, balavardhana property, which helps in samprapti vighatana of the disease. In present scenario Kala Basti mentioned by Acharya Charaka is widely practiced, while Kala Basti mentioned by Kashyapaand Vagbhataare usually not in practice, as in today’s era everyone has busy schedule, hence an attempt is made to evaluate the effect of these two patterns of Kala Basti having maximum number of Anuvasana Basti in minimum duration using Panchamoolabalasiddha Ksheera Basti in Janu Sandhigatavata.