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Correlation between alcohol concentration and an electroencephalogram (EEG) measure of anaesthetic depth

Not Applicable
Completed
Conditions
The impact of increasing alcohol on BIS (a measure of EEG activity used as a surrogate for anaesthetic depth)
Anaesthesiology - Other anaesthesiology
Registration Number
ACTRN12613000801718
Lead Sponsor
niversity of Auckland
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
20
Inclusion Criteria

Anaesthetic Trainees (age between 25 and 40 years) who have completed their clinical duties on a Friday afternoon and are not rostered to work for at least 24 hours.

Exclusion Criteria

History of epilepsy; currently taking any sedating medication including analgesics such as codeine and opioids, benzodiazepines, anti-epileptics and sleeping medications; history of liver disease or impaired liver function; currently pregnant.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Correlation between end-expired (breathalyser) alcohol concentration and BIS.[Baseline (before drinking) and then every hour over four hours]
Secondary Outcome Measures
NameTimeMethod
Correlation between blood alcohol concentration and BIS. [Four hours after starting drinking (at study end)];Agreement and correlation between Anaesthetic Trainees’ predicted blood alcohol concentration and measured blood alcohol concentration[At each breath alcohol concentration reading (1, 2, 3 and 4 hours)]
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