A study to measure the accuracy of a new test for the diagnosis of melanoma

Not Applicable

Completed

• Conditions: Melanoma; Cancer; Malignant melanoma of skin, unspecified

• Registration Number: ISRCTN17674794
• Lead Sponsor: niversity of Kansas Medical Center

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35672262/ (added 20/09/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-03
• Study Completion: 2022-06-30
• Last Update Posted: 3 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 143

Inclusion Criteria

1. Pathology sample of a primary pigmented skin lesion
2. PRAME immunohistochemistry performed on that sample prior to final diagnosis
3. MART1 immunohistochemistry performed on that sample prior to final diagnosis

Exclusion Criteria

1. Uncertain final diagnosis (e.g., MELTUMP)
2. Re-excision
3. Spindle cell melanoma
4. Desmoplastic melanoma
5. Metastatic melanoma
6. Nonmelanocytic lesion
7. Missing slides
8. Unreadable PRAME or MART1 slides due to technical error

Study & Design

• Study Type: Observational
• Study Design: Not specified