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临床试验/ACTRN12619001244190
ACTRN12619001244190已完成1 期

Comparison of administration of 0.9% Sodium Chloride solution versus Plasma-Lyte 148 versus Compound Sodium LacTate Solution in children admitted to PICU – a randomised controlled trial

niversity of Queensland0 个研究点目标入组 524 人开始时间: 2019年9月9日最近更新:

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
524

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Treatment
盲法
Open (masking not used)

入排标准

年龄范围
Days 至 16 Years(—)
性别
All

入选标准

  • 1. All patients – birth to an age of less than 16 years - admitted to the Paediatric Intensive Care Unit (and)
  • 2. Attending clinician decides that intravenous fluid therapy is required
  • 3. Admission Na >130mmol/L
  • 4. New admissions to ICU within the last 24 hours

排除标准

  • 1. Age greater than or equal to 16 years.
  • 2. Patients admitted with a cardiac condition.
  • 3. Received intravenous fluid therapy for >4 hours in PICU.
  • 4. Patients admitted to the ICU with disease-specific protocols that necessitate specific fluid requirements such as: the treatment of burns; following liver transplantation surgery; post renal transplant surgery; diabetic ketoacidosis.
  • 6. Patients with traumatic brain injury or those considered at risk of developing cerebral edema
  • 7. Patients with pre-existing kidney disease (chronic kidney disease as defined by KDIGO criteria or under the ongoing care of a nephrologist)
  • 8. Oncology patients who need hyperhydration.

研究者

发起方
niversity of Queensland

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