ACTRN12619001244190已完成1 期
Comparison of administration of 0.9% Sodium Chloride solution versus Plasma-Lyte 148 versus Compound Sodium LacTate Solution in children admitted to PICU – a randomised controlled trial
niversity of Queensland0 个研究点目标入组 524 人开始时间: 2019年9月9日最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 524
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- Days 至 16 Years(—)
- 性别
- All
入选标准
- •1. All patients – birth to an age of less than 16 years - admitted to the Paediatric Intensive Care Unit (and)
- •2. Attending clinician decides that intravenous fluid therapy is required
- •3. Admission Na >130mmol/L
- •4. New admissions to ICU within the last 24 hours
排除标准
- •1. Age greater than or equal to 16 years.
- •2. Patients admitted with a cardiac condition.
- •3. Received intravenous fluid therapy for >4 hours in PICU.
- •4. Patients admitted to the ICU with disease-specific protocols that necessitate specific fluid requirements such as: the treatment of burns; following liver transplantation surgery; post renal transplant surgery; diabetic ketoacidosis.
- •6. Patients with traumatic brain injury or those considered at risk of developing cerebral edema
- •7. Patients with pre-existing kidney disease (chronic kidney disease as defined by KDIGO criteria or under the ongoing care of a nephrologist)
- •8. Oncology patients who need hyperhydration.
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