Universal Biospecimen Collection Protocol for Extra Material From Clinical Pulmonary Procedures

Recruiting

• Conditions: Pulmonary

• Registration Number: NCT07218939
• Lead Sponsor: M.D. Anderson Cancer Center

Brief Summary

The goal of this study is to develop a biospecimen collection protocol for unused biospecimens from pulmonary procedures in order to facilitate research across many different areas of pulmonary medicine and mitigate the pulmonary morbidity experienced by patients with cancer.

Detailed Description

Primary objectives:

To assemble a tissue/blood bank biorepository for laboratory translational research by collecting extra samples of bronchoalveolar lavage, pleural fluid, blood or other residual tissue obtained during normally scheduled clinical procedures for the evaluation of pulmonary toxicity

To collect basic data on patient data and suspected pulmonary toxicity to cross-reference eligible biospecimens

Study Timeline

• Status Verified: 2025-10
• Study Start: 2025-10-08
• Study First Submitted: 2025-10-17
• Study First Submitted QC: 2025-10-17
• Last Update Submitted: 2025-10-17
• Study First Posted: 2025-10-21
• Last Update Posted: 2025-10-21
• Primary Completion: 2030-12-01
• Study Completion: 2032-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 12000

Inclusion Criteria

All patients over the age of 18, who are seen in the Cardiopulmonary Center and are undergoing pulmonary procedures

Exclusion Criteria

Pregnant women and prisoners

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Safety and Adverse Events (AEs)	Through study completion; an average of 1 year	Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Trial Locations

Locations (1)

The University of Texas M. D. Anderson Cancer Center; 🇺🇸 Houston, Texas, United States