KCT0003730
Recruiting
未知
The diagnosis, clinical characteristics and prognostic factor of Fabry disease in the Korean population: A multicenter, prospective study
ConditionsDiseases of the circulatory system
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of the circulatory system
- Sponsor
- Korea University Anam Hospital
- Enrollment
- 2000
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion criteria
- •1\. Conventional screening criteria: severe left ventricular hypertrophy or suspicious of HCM (Interventricular septal thickness \>13mm in transthoracic echocardiography)
- •2\. Unexplained left ventricular hypertrophy (left ventricular mass index \= 115 g/m2 in men, \= 95 g/m2 in women)
- •With at least one of following criteria
- •\- Diastolic dysfunction
- •Diastolic dysfunction is diagnosed by American Society of Echocardiography recommendation.
- •? At least 2 positive findings as followings:
- •1\) Averaged E/e’ \>14
- •2\) Septal e’ \<7cm/sec
- •3\) Tricuspid regurgitant peak velocity \>2\.9m/sec
Exclusion Criteria
- •Exclusion criteria
- •1\. Left ventricular hypertrophy which is caused by other mechanisms, including aortic stenosis, hypertension or diabetes.
- •2\. Multiple myeloma
- •3\. Congenital heart disease
- •4\. Previous cardiac surgery
Outcomes
Primary Outcomes
Not specified
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