Effect of Wuweixiaodu Decoction on Clinical Efficacy and Inflammatory Factors of Acute Gouty Arthritis
- Conditions
- Gouty Arthritis
- Registration Number
- ITMCTR2100004981
- Lead Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medicine University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Voluntarily sign the informed consent form before the trial-related activities, be able to understand the procedures and methods of the trial, and be willing to strictly abide by the clinical trial protocol to complete the trial;
2. Age between 18-75 years old, male or female;
3. Patients who meet the 1977 or 2015 ACR (American College of Rheumatology) classification and diagnosis criteria for gout, and have been identified by professional doctors as moderate to severe activity in the acute arthritis stage, and the TCM differentiates the disease as damp-heat accumulation type.
1. Persons who are considered by researchers to have poor compliance and affect the evaluation of drug safety and effectiveness; persons who abuse drugs;
2. Patients with renal failure and liver damage (transaminase greater than three times the upper limit of normal);
3. Those who are allergic to various drugs in the program;
4. Patients with a history of chronic heart disease, malignant tumors, recurrent infectious diseases, peptic ulcers, and low blood levels;
5. Suffering from other diseases that may confuse gouty arthritis, such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, systemic lupus erythematosus, Sj?gren's syndrome and other diseases;
6. Pregnant women and lactating women.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method C-reactive protein;interleukin-1ß;erythrocyte sedimentation rate;Cytokines IL-2, 4, 6, 10, TNF-a, IL-10, IFN-?;Uric acid;
- Secondary Outcome Measures
Name Time Method