Effect of Rosiglitazone

Not Applicable

Completed

• Conditions: Healthy

• Registration Number: NCT00285142
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

To evaluate :

* acute effects of a single dose of 8 mg rosiglitazone (therapeutic dose)

* on insulin secretion and

* insulin sensitivity in 12 healthy male subjects.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-06
• Study Completion: 2004-11
• Status Verified: 2006-01
• Study First Submitted: 2006-01-31
• Study First Submitted QC: 2006-01-31
• Study First Posted: 2006-02-01
• Last Update Submitted: 2019-06-07
• Last Update Posted: 2019-06-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• BMI between 18.0 and 24.0

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
insulin response and insulin sensitivity assessed by 2-hours 10 mmol/l hyperglycemic clamp, started 45 min after treatment intake

Secondary Outcome Measures

Name	Time	Method
basal glycemia and insulinemia
insulin clearance
tolerance

Trial Locations

Locations (1)

Centre d'Investigation Clinique; 🇫🇷 Montpellier, France