Repetitive Transcranial Magnetic Stimulation in Patients With Hemiplegic Stroke
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 48
- 试验地点
- 3
- 主要终点
- Keyboard tapping test
研究概览
简要总结
Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited. The development of new treatment strategies is essential. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method to stimulate the focal area of the brain for restoring brain function. The aim of this study is to investigate the therapeutic effect of rTMS on the motor recovery in patients with hemiplegic stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •stroke patients with motor weakness
- •Medical research council (MRC) grade 0-4
- •More than 2 weeks after stroke onset
- •Age 18 years and older
- •Able to provide consent for the protocol
排除标准
- •History of previous symptomatic stroke
- •pregnant women
- •Persons with surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), intracardiac lines that may pose a physical hazard during magnetic stimulation will also be excluded
- •Patients with history of seizure disorder or epilepsy
- •Subjects without the capacity to give informed consent
结局指标
主要结局
Keyboard tapping test
时间窗: 1 day
Participants will be asked to tap a key of a computer keyboard as fast as possible in five seconds. They will be asked to do three times. We will measure the number of tapping. The primary outcome will be the averaged data of the numbers.This will be done before and after 5-day rTMS intervention.
次要结局
未报告次要终点
研究者
Suk Yun Kang
MD, PhD
Dongtan Sacred Heart Hospital