A Study of the Effect of Plasmaexchange in Patients With Acute Liver Failure
Not Applicable
Completed
- Conditions
- Acute Liver Failure
- Registration Number
- NCT00950508
- Lead Sponsor
- Rigshospitalet, Denmark
- Brief Summary
The aim of this study is to examine if high-volume plasma exchange has a positive effect on mortality in patients with acute liver failure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 183
Inclusion Criteria
- Patients with acute liver failure in encephalopathy grade 2-4
Exclusion Criteria
- alcoholic hepatitis
- primary non function liver graft or graft dysfunction
- known chronic liver disease
- known malignancies
- clinical suspicion of brain death
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method mortality at day 3, day 7
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
Department of Hepatology, Rigshospitalet
🇩🇰Copenhagen, DK, Denmark
Department of Transplantation and Liver Surgery, Helsinki University Hospital
🇫🇮Helsinki, Finland
Institute of Liver Studies, King's College Hospital
🇬🇧London, United Kingdom
Department of Hepatology, Rigshospitalet🇩🇰Copenhagen, DK, Denmark