A clinical trial to study Intracameral Amphotericin B with topical antifungal drugs and topical antifungals alone in management of Deep Fungal Keratitis
Phase 3
Completed
- Registration Number
- CTRI/2011/091/000107
- Lead Sponsor
- R P Centre, AIIMS, New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 45
Inclusion Criteria
Smear- positive deep fungal keratitis with hypopyon whho did not respond to topical natamycin 5 %and amphotericin B 0.15 %
Exclusion Criteria
One-eyed patients, children < 12 years of age, and cases with keratitis limited to anterior 1/3rd of stroma and with concurrent sclera involvement
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to Epithelialization and time to resolution of ulcerTimepoint: day1, day3, day7, day 10,day 14, month1 , month 3
- Secondary Outcome Measures
Name Time Method best corrected visual acuityTimepoint: day1, day3, day7, day 10,day 14, month1 , month 3