se of Platelet Rich Plasma associated with Ozone Therapy in skin rejuvenatio

Not Applicable

Recruiting

• Conditions: Skin Aging; G13.750

• Registration Number: RBR-5x9n573
• Lead Sponsor: niversidade Brasil

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-07-11
• Last Update Posted: 26 July 2023
• Study Completion: 2025-06-06

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

women; age range of 40 and 60 years; phototype II to IV according to the Fitzpatrick scale; presence of signs of facial photoaging grade II to IV according to the Glogau scale; blood count with normal platelet count (150,000 to 350,000 uL); consent to participate in the study to sign the informed consent;

Exclusion Criteria

smokers; pregnant or breastfeeding women; history of neoplasia; ablative chemical or physical peeling in the last 6 months; use of botulinum toxin or fillers with facial implants with absorbable material in the last six months; performance of surgical procedures (rhytidoplasty and/or blepharoplasty); patient unable to use photoprotection throughout the treatment period; patients with a history of keloids or hypertrophic scarring; patients with infected or inflamed skin lesion on the face in the last 12 months; underlying diseases such as uncontrolled systemic arterial hypertension; renal liver disease; hematological (coagulopathies and/or purpura, glucose 6-phosphate deficiency); inflammatory; rheumatological; with diabetes; platelet count below 150,000/uL; of hypersensitivity to ozone therapy treatment; refusal to sign the informed consent form; still, the discontinuity criteria were established: withdrawal of the participants; two consecutive absences; present any disorder/infection that implies the use of antibiotics throughout the study;

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate and compare the effects of Platelet Rich Plasma (PRP) and its association with ozone therapy on skin aging using the Global Aesthetic Improvement Scale

Secondary Outcome Measures

Name	Time	Method
Evaluate self-esteem using the Brazilian version of the Rosenberg Self-Esteem Scale ;Evaluate treatment satisfaction through the Perception of Global Effect