A Randomised Comparative Clinical Study to Evaluate the Efficacy of Paribhadradi pralepa and Paribhadradi ointment in the management of Janu Sandhigata Vata ( Knee Osteoarthritis)
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The expected outcome of the study would ideally demonstrate the efficacy of both
研究概览
简要总结
In this study, patients will be recruited from the Outpatient Department of Kaya Chikitsa at M.C. DAV Hospital in Jalandhar. Selection will be based on specific inclusion and exclusion criteria. Prior to enrollment, routine investigations will be conducted to ensure eligibility for participation in the study.This study aims to compare the efficacy of Paribhadradi Pralepa and Paribhadradi Ointment in managing symptoms of knee osteoarthritis, focusing on pain relief, functional improvement, and quality of life. Knee osteoarthritis (Janu Sandhigata Vata) is a prevalent condition that causes pain and disability. Traditional Ayurvedic treatments,( Paribhadradi Pralepa and Paribhadradi Ointment )comparative efficacy requires systematic evaluation..Paribhadradi Pralepa & Paribhadradi Ointment will be applied on Knee joints only at night and keep it on until the following morning, approximately eight hours.The findings of proposed study will support the integration of Ayurvedic treatments in the management of osteoarthritis and warrant further investigation into long-term effects and mechanisms of action
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 40.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients in the age group of 40 to 70 years of either sex.
- •Patients having signs and symptoms of Janusandhigata Vata of Shotha (edema), Vatapurnadriti Sparsha (on palpation revealed as air filled bag) and pain with Prasaran (extension) and Akunchan (flexion) movements.
- •Patients having chronicity of disease Janusandhigata Vata (KOA) for less than 5 years.
- •Patients willing to sign consent form for the clinical trial.
- •Kellgren Lawrence (Radiological scale) of e†≥2 13.
排除标准
- •Patients below 40 years and above 70 years of age.
- •Patients of Rheumatoid arthritis, Ankylosing and traumatic arthritis.
- •Patients suffering from paralysis, muscular dystrophy, polio or bony deformities.
- •Patients having systemic conditions such as Tuberculosis, Brucellosis, Osteomyelitis, Gouty Arthritis, Psoriatic Arthritis and Systemic Lupus Erythematosus
- •Patients having neoplasm of spine and other complicated diseases like CCF, DM, Uncontrolled HTN, Unstable Angina, Recent MI etc.
- •Patients using anti-inflammatory medicines including Allopathic medicine and AYUSH medicines.
结局指标
主要结局
The expected outcome of the study would ideally demonstrate the efficacy of both
时间窗: 15 days
Paribhadradi Pralepa and Paribhadradi ointment in improving pain, functionality, and
时间窗: 15 days
quality of life in patients with knee osteoarthritis, while also ensuring their safety and
时间窗: 15 days
tolerability profile.
时间窗: 15 days
次要结局
- Reduction in hospital visits after completion of trial(30 days)
研究者
Dr Chander Shekhar Sharma
Dayanand Ayurvedic College, Jalandhar city,Punjab