Study to Find the Percentage of Cases Retaining COVID-19 IgG Antibodies 45-65 After They Have Tested Positive

Completed

• Conditions: Covid19
• Interventions: Diagnostic Test: Repeat SARS-CoV-2 IgG antibodies at 45-65 days

• Registration Number: NCT04605952
• Lead Sponsor: Tata Main Hospital

Brief Summary

As a serosurveillance measure asymptomatic employees of an industrial workforce Jamshedpur (India) were tested for COVID-19 IgG antibodies. Of the tested employees who were positive for COVID-19 IgG antibodies the study aimed to find the percentage of cases who retained their COVID-19 IgG antibodies 45-65 days after initially testing positive.

Detailed Description

As a serosurveillance measure, 3296 asymptomatic employees of an industrial workforce Jamshedpur (India) were tested for COVID-19 IgG antibodies specific for the spike subunit antigen by the ErbaLisa COVID-19, Erba Corporate Services (United Kingdom) between 28th June and 15th July 2020.

The cases who tested positive for COVID-19 IgG antibodies were repeat tested for the presence of COVID-19 IgG at 45-65 days after initially testing positive. This was done with the aim of finding out the percentage of cases retaining their IgG antibodies at 45-65 days of initially testing positive.

Study Timeline

• Study Start: 2020-07-01
• Primary Completion: 2020-08-30
• Study Completion: 2020-08-30
• Status Verified: 2020-10
• Study First Submitted: 2020-10-23
• Study First Submitted QC: 2020-10-27
• Last Update Submitted: 2020-10-27
• Study First Posted: 2020-10-28
• Last Update Posted: 2020-10-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 201

Inclusion Criteria

SARS-CoV-2 IgG antibody positive between 28th June and 15th July 2020

Exclusion Criteria

SARS-CoV-2 IgG antibody negative between 28th June and 15th July 2020

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
SARS-CoV-2 IgG antibody positive between 28th June to 15th July 2020	Repeat SARS-CoV-2 IgG antibodies at 45-65 days	As a serosurveillance measure, 3296 asymptomatic employees of an industrial workforce Jamshedpur (India) were tested for SARS-CoV-2 IgG antibodies specific for the spike subunit antigen by the ErbaLisa COVID-19, Erba Corporate Services (United Kingdom) between 28th June and 15th July 2020. All those who initially tested SARS-CoV-2 IgG antibody positive were retested at 45-65 days

Primary Outcome Measures

Name	Time	Method
Percentage of cases retaining SARS-CoV-2 IgG antibodies at 45-65 days	45-65 days	Percentage of cases retaining SARS-CoV-2 IgG antibodies at 45-65 days

Trial Locations

Locations (1)

Dr.Deb Sanjay Nag; 🇮🇳 Jamshedpur, Jharkhand, India