DRKS00008765已完成未知
Dopaminergic and cholinergic modulation of oculomotor control during saccades
Translational Neuromodeling Unit, Institut für Biomedizinische Technik, Universität Zürich und ETH Zürich0 个研究点目标入组 150 人开始时间: 2015年6月11日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 40 Years（—）
- 性别
- Male
入选标准
- •Age: =18 and =40 years
- •European ancestry
- •Written informed consent
- •Consent to adhere to the study protocol
- •Ability to adhere to the study protocol
排除标准
- •Serious past or present brain disease, brain injury or brain surgery
- •Any neurological or psychiatric disorders (past or present)
- •Current psychoactive medication
- •Daily nicotin use
- •Daily alcohol use > 2 units per day on average (1 unit = 3 dl beer = 1 dl wine)
- •Current use of recreational drugs
- •History of drug abuse
- •Any current severe medical condition
- •Additional exclusion criteria for the pharmacological study branches:
- •Tachy- or bradycardia (normal range 55-100 bpm), cardiac arrhythmia and/or QTc-time >430 ms
- •History of severe kidney or liver disorder
- •Prostate or bladder disorder
- •Asthma or other obstructive respiratory disease
- •Current medication known to interact with levodopa, benserazide, or galantamine
- •Allergy to lactose, levodopa, benserazide, or galantamine
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