MedPath

Connect to Protect Partnerships for Youth Prevention Interventions: Phase II

Completed
Conditions
HIV Infection
Registration Number
NCT00103896
Lead Sponsor
University of North Carolina, Chapel Hill
Brief Summary

This is Phase II of a three stage project whose overall goals are to develop viable community-based HIV prevention interventions and to form and maintain the necessary community collaborations to support such Adolescent Trials Network (ATN) research activities.

This phase will describe specific locations within high-risk areas where youth, ages 12-24, spend time. HIV risk behaviors, social networking patterns and HIV prevalence among youth at these venues will be assessed by administering anonymous computerized interviews to eligible and willing youth. This information will be shared with community partners during scheduled working group meetings.

Detailed Description

This is Phase II of a three stage project whose overall goals are to develop viable community-based HIV prevention interventions and to form and maintain the necessary community collaborations to support such ATN research activities.

During this phase, each ATN site will gather additional information within high-risk areas and solicit community partner input to ultimately pinpoint the specific locations where at-risk youths, ages 12-24, may be recruited for interventions. This will be done by the following methods:

Venues will be identified by HIV+ youth at the ATN site by participation in an anonymous computerized interview. Site staff will then perform brief venue interviews (BVIs) at selected venues to assess the potential yield of youths 12-24 years old. Community partners will also provide the site staff with information on known high-risk venues. High-risk venues will further be identified by the results of anonymous computerized interviews and HIV assays obtained from eligible and willing youth participants at the venues. The interviews will gather information on HIV risk behaviors, social networking patterns and HIV prevalence among youths at these venues. This information will be shared with community partners during scheduled working group meetings.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
16706
Inclusion Criteria

Index Subjects:

  • Documented HIV-infection
  • Acquisition of HIV after age 9 years
  • Verbal confirmation of 12-24 years of age
  • Verbal report of having engaged in sexual activity (vaginal, anal and/or oral sex) within the past 12 months
  • Ability to understand and willingness to provide informed consent/assent

BVI subjects:

  • Youths who appear to be 12-24 years old

HIV Serosurvey subjects at the venues:

  • Verbal confirmation of 12-24 years of age
  • Verbal report of having engaged in sexual activity (vaginal, anal and/or oral sex) within the past 12 months
  • Ability to understand and willingness to provide informed consent/assent
Read More
Exclusion Criteria
  • Visibly distraught and/or emotionally unstable (i.e. depressive mood, exhibiting manic, suicidal or violent behavior, etc.)
  • Visibly intoxicated or under the influence of psychoactive agents
  • Clinically presents as acutely ill
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Assess the characteristics of the community-researcher partnershipsOne time assessment at 10 months

The outcome measure will be assessed by conducting interviews with C2P staff and their community partners. Questionnaires will be completed by both parties and detailed documentation kept.

Ascertain specific community venues where at-risk youth can be recruited for interventions within the high-risk areas identified in the first Phase of the studyOne time assessment at 10 months

The outcome measure will be assessed using results from: (a) Phase I mapping; (b) Phase II interviews with HIV-infected youth; and (c) Phase II Brief Venue Interviews (BVIs). Input from community partners and ethnographic procedures will add critical information.

Describe HIV risk behaviors of adolescents and young adults recruited from targeted venuesOne time assessment at 10 months

The outcome measure will be assessed by conducting HIV serosurveys at each venue identified with youth whose HIV status is unknown.

Describe social networks of adolescents and young adults recruited from targeted venuesOne time assessment at 10 months

The outcome measure will be assessed by conducting HIV serosurveys at each venue identified with youth whose HIV status is unknown.

Describe HIV seroprevalence of adolescents and young adults recruited from targeted venuesOne time assessment at 10 months

The outcome measure will be assessed by conducting HIV serosurveys at each venue identified with youth whose HIV status is unknown.

Assess quality of the community-researcher partnershipsOne time assessment at 10 months

The outcome measure will be assessed by conducting interviews with C2P staff and their community partners. Questionnaires will be completed by both parties and detailed documentation kept.

Assess outcomes of the community-researcher partnershipsOne time assessment at 10 months

The outcome measure will be assessed by conducting interviews with C2P staff and their community partners. Questionnaires will be completed by both parties and detailed documentation kept.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (15)

Childrens Hospital of Los Angeles

🇺🇸

Los Angeles, California, United States

Univ of Califormia at San Francisco

🇺🇸

San Francisco, California, United States

Stroger Hospital of Cook County

🇺🇸

Chicago, Illinois, United States

Children's Hospital National Medical Center

🇺🇸

Washington, District of Columbia, United States

Children's Diag. and Treatment Center

🇺🇸

Ft. Lauderdale, Florida, United States

University of Maryland

🇺🇸

Baltimore, Maryland, United States

Tulane Medical Center

🇺🇸

New Orleans, Louisiana, United States

Mount Sinai Medical Center

🇺🇸

New York, New York, United States

Childrens' Hospital of Boston

🇺🇸

Boston, Massachusetts, United States

Children's Hopsital of Philadelphia

🇺🇸

Philadelphia, Pennsylvania, United States

University Pediatric Hospital

🇵🇷

San Juan, Puerto Rico

USF Peds Div. of Infectious Disease

🇺🇸

Tampa, Florida, United States

University of Miami

🇺🇸

Miami, Florida, United States

Montefiore Medical Center, Adolescent AIDS Program

🇺🇸

Bronx, New York, United States

UCSD Mother, Child & Adolescent HIV Program

🇺🇸

San Diego, California, United States

© Copyright 2025. All Rights Reserved by MedPath